R40, R41 and R42 are each independently selected from the group consisting of R38 is COOR39, Image, NH2, or amino acid R32 is selected from the group consisting of naturally occurring amino acids,Īnd C6H10O5 carbohydrates, C12H22O11 and C6H10O5 carbohydrates which carryįrom 1 to 3 amino substituents, (saccharide)q, and C(O)R33 R6 is selected from the group consisting of benzyl, hydroxybenzyl, (C1-Ĭ3)alkoxybenzyl, halohydroxybenzyl, dihalohydroxybenzyl, halo(C1-Ĭ3)alkoxybenzyl, and dihalo(C1-C3)alkoxybenzyl group R5 is H or OH or R4 and R5 may be taken together to form a double bond R1 is OH and R2 is halogen or R1 is halogen and R2 is OR31, provided that Halogen, a naphthyl group, a furyl group, an indolyl group, a pyrrolyl group,

ELI LILLY AND COMPANY (United States of America)Īr is a phenyl group, a phenyl group substituted with a C1-C12 alkyl, C2-C12Īlkenyl, C2-C 12 alkynyl, NR51R52, OR53, a phenyl group substituted with a.

WAYNE STATE UNIVERSITY (United States of America).

UNIVERSITY OF HAWAII (United States of America).

RAY, JAMES EDWARD (United States of America).

VASUDEVAN, VENKATRAGHAVAN (United States of America).

TOTH, JOHN ELDON (United States of America).

PATEL, VINOD FRANCIS (United States of America).

NORMAN, BRYAN HURST (United States of America).

MUNROE, JOHN EDWIN (United States of America).MOORE, RICHARD ELLIOTT (United States of America).MOHER, ERIC DAVID (United States of America).MARTINELLI, MICHAEL JOHN (United States of America).GOTTUMUKKALA, SUBBARAJU VENKATA (India).

EHLHARDT, WILLIAM JOSEPH (United States of America).AL-AWAR, RIMA SALIM (United States of America).(51) International Patent Classification (IPC):

Free for mac instal Draw.io 21.7.5